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110 E Greenville Street, Anderson
$1,950,000
Endless investment potential on one of Anderson's most iconic corners! Nestled in one of Anderson’s most prominent and well-trafficked locations, this multi-building, multi-tenant portfolio property offers an unparalleled opportunity for business owners and investors alike. Occupying nearly half of one of the city’s most iconic blocks, this property is a cornerstone of Anderson’s bustling commercial hub. Its strategic location at the intersection of E Greenville Street and Main Street ensures maximum visibility and accessibility, making it an ideal destination for retail, professional services, or dining establishments. Spanning 1.21 acres with over 14,000 square feet of versatile space, the property features multiple buildings designed to accommodate a range of commercial needs. Positioned at the corner of E Calhoun and McDuffie Streets, the site also enjoys frontage along E Greenville Street, with red-light access on three sides to ensure seamless traffic flow for patrons and clients. The property’s layout offers flexibility, allowing tenants to customize the spaces to suit their specific requirements, whether they are a retail vendor, restaurateur, or professional office provider. The visibility and accessibility of this property are unmatched. Its location within the heart of Anderson places it amidst thriving businesses, providing a steady stream of potential customers. The property’s position on key city streets ensures consistent exposure to both pedestrian and vehicle traffic, making it a highly desirable site for a range of ventures. Whether you’re looking to establish a flagship retail store, expand a professional office portfolio, or create a dining destination in one of South Carolina’s fastest-growing cities, this property offers the space, location, and flexibility needed to bring your vision to life. With its prime location and multi-tenant potential, this commercial listing is a rare opportunity to secure a presence in the heart of Anderson’s vibrant economic landscape. Don’t miss your chance to be part of this thriving community.

110 E Greenville Street, Anderson
2000 E River Street, Anderson
$4,950,000
DEVELOPERS DREAM! Welcome to Rocky River Plantation, formerly known as “Valley View,” a Southern masterpiece along the Rocky River. Step back in time and immerse yourself in the elegance of the early 20th century with this stunning Greek Revival estate, located at 2000 East River Street, Anderson, SC. Built in 1913 by Mr. Seybt, this historic home is a true architectural gem and a rare opportunity to own a piece of Southern history. Nestled on 62.34 acres of picturesque land, Rocky River Plantation seamlessly combines timeless grandeur with modern potential. The 4,000-square-foot home is a commanding structure featuring ten spacious rooms, two room-sized halls, a basement, and a permanent staircase leading to two attic rooms. The first floor boasts soaring 11-foot ceilings, while the second floor stands at an impressive 10 feet. The craftsmanship is impeccable, with two-inch slash pine floors intricately laid in patterns and architectural details such as front-facing columns and additional columns within the grand entrance hall. A large wrap-around porch further enhances the home’s charm, offering the perfect space to enjoy serene views and Southern hospitality. Designed by architects Joe Casey and Charles W. Fant, Sr., this home has been cherished by notable owners, including former U.S. Congressman John C. Taylor and his family. Beyond the house itself, the expansive grounds offer over 2,000 feet of frontage along the scenic Rocky River, providing breathtaking natural beauty and abundant recreational opportunities. Additionally, the property boasts 2,600 feet of road frontage along US Highway 178, offering unparalleled access and visibility. Located in the heart of Anderson, South Carolina, Rocky River Plantation is centrally positioned at the intersection of US Highway 178 and US Highway 29. The property is unzoned and unrestricted, with all major utilities in place, including sewer, high-KVH power, a 10-inch natural gas line, fiber, and a 12-inch water line. These features make the estate a prime redevelopment site for multi-family residential, commercial, or industrial projects. Rocky River Plantation stands as a testament to enduring beauty and refined Southern living. Whether you dream of restoring this historic treasure to its original glory or envisioning a modern redevelopment that harnesses its potential, this estate offers a truly unique canvas for your vision.

2000 E River Street, Anderson
3.8 Acs Pearman Dairy 3.80 Road, Anderson
$499,000
Sewer on property can have back entrance onto Doubletree. Ideal for shopping center, grocery store, auto dealer, boat retail, Ideal for most any type retail shopping on front, warehouses on back. more than 15,000 autos pass this property each day.

3.8 Acs Pearman Dairy 3.80 Road, Anderson
9 Doubletree Drive, Anderson
$270,000
This is an ideal location for apartments, single family houses, commercial development, industrial development. Good area for Recreational; development. Sewer is in the area but not sure we can get gravity flow to sewer. $22,500 per acre.

9 Doubletree Drive, Anderson
1.45 ac Pearman Dairy Road, Anderson
$325,000
Sewer on property. Water on Pearman Dairy Rd. can add 2.357 acres for larger tract. Great site for shopping center. Can have a back outlet onto Double Tree. Grocery store site, auto dealer site by adding 2.357 acres for a total of 3.80 acres with rear access. Great value.

1.45 ac Pearman Dairy Road, Anderson
16 ac Pearman Dairy Road, Anderson
$480,000
Ideal location for recreation development, driving range golf, Drive in Theater, miniature golf, apartments, single family, industrial development. Sewer on Doubletree Drive and 28 Bypass.

16 ac Pearman Dairy Road, Anderson
10.50 Ac. Royal American Road, Anderson
$850,000
10.5 acres fronting I-85. More than 500 feet road frontage Great visibility to I-85 and US 76. More that 55,000 vehicles pass this commercial property each day. All utilities are available. Great for Motel, Hotel, Restaurants, Car Dealership, Boat Dealership, Class A Office Space and Retail Development. Possible Multi Family use.

10.50 Ac. Royal American Road, Anderson
Lot 113 Hidden Lake Drive, Anderson
$59,900
Great buildable lot on LAKE HARTWELL in a cove in Hidden Lakes Subdivision. Drive by and see this lot today!!

Lot 113 Hidden Lake Drive, Anderson
3105 Hwy 29 Highway S Unit Lot 16 - 11 Wood Forest L, Anderson
$2,200,000
Great old farm house on 94 ac. of land with a stream running across the entire width of front parcel. Front parcel is both pasture and timber. Listing also includes 28/37 ac. of timber on the backside of the Hwy 29 site which fronts Woodforest Ln. This would also be a great site for industrial business.

3105 Hwy 29 Highway S Unit Lot 16 - 11 Wood Forest L, Anderson
Lot9 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot9 N 29 Highway, Anderson
Lot R-1-A Destination Boulevard, Anderson
$585,000
Desirable high traffic property located right at I-85 and US 76-28 (Exit 19A) intersection. All Utilities are available. Great location for restaurant, corporate office, shopping plaza, wedding venue and many other business locations. More than 80,000 combined vehicles pass here each day on I-85 and Hwy 76 (Clemson Blvd) Exit 19B heading north 15 miles takes you to Clemson University, Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, boat ramps, shopping centers, hotels, fast food and dine in restaurants, residential home and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others. LOTS R-1-A AND R-1-B + R 2 (BEING SOLD TOGETHER) CAN BE PURCHASED TOGETHER FOR A TOTAL OF 6.06 ACRES ALL FOR ASKING PRICE OF $1,499,800.

Lot R-1-A Destination Boulevard, Anderson
Lot4 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot4 N 29 Highway, Anderson
Lot5 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot5 N 29 Highway, Anderson
Lot10 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot10 N 29 Highway, Anderson
Lot8 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot8 N 29 Highway, Anderson
Lot3 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot3 N 29 Highway, Anderson
105 Destination Boulevard, Anderson
$949,000
249' along I-85! Desirable high traffic property located right at I-85 and US 76-28 (Exit 19A) intersection. All utilities and storm drainage work complete with public road ready to access your business. Utilities available at property are water, sewer, electric and gas. Easy to access the interstate. Great location for restaurant, corporate office, shopping plaza, wedding venue and many other business ventures! More than 80,000 combined vehicles pass here each day on I-85 and Hwy 76 (Clemson Blvd) Exit 19B heading north 11 miles takes you to Clemson University and 6.5 Miles heading southwest on Hwy 76/Clemson Blvd. takes you to Anderson University. Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, Portman Marina, boat ramps, shopping centers, hotels, fast food and dine in restaurants, residential homes and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others. On Destination Blvd: Hilton Garden Inn, Fuddruckers, AJ's Bar and Grill - Within a mile of Panera's, Texas Roadhouse, Olive Garden, Longhorn, Hardees, Bojangles, Chick Fil-A, Chilis, and more! On the other side of Interstate: Waffle House, Wendy's, McDonalds, Arbys, Holiday Inn Express, Subway, Outback, Hooters, Wild Wings, Fairfield Inn, Country Inn & Suites, Comfort Inn & Suites, Starlight Movie Theater, Hampton Inn, and Cracker Barrel.

105 Destination Boulevard, Anderson
109 W Calhoun Street, Anderson
$154,500
Former lawyers office and stenographer office. Located in the heart of downtown Anderson, this 2,500 sq. ft. heated commercial space offers an exceptional opportunity in a rapidly growing area. Features include a brand-new city-installed parking lot and lighting with rear access. Ideal for a law office, retail shop, restaurant, or virtually any business venture you can envision. Within walking distance to local retail shops, restaurants, the courthouse, and the farmers market—plus just steps away from a new 167-unit apartment development with commercial parcels along the front. Downtown Anderson is expanding rapidly, and it’s becoming harder to find commercial land at this price point. Don’t miss your chance to secure a prime location in this vibrant community. Owner financing is available.

109 W Calhoun Street, Anderson
Lot6 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot6 N 29 Highway, Anderson
Lot7 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot7 N 29 Highway, Anderson
Lot2 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot2 N 29 Highway, Anderson
141 Extended Lane, Anderson
$750,000
Great unrestricted commercial property with 11.35 acres of unlimited possibilities. The tract is located on Michelin Blvd near Westside High School and has a lot to offer to a wide range of buyers. With over 1,100 feet of paved road frontage, access to public water and sewer, access to high-speed internet, this makes a great property for commercial and/or residential development.

141 Extended Lane, Anderson
Lot1 N 29 Highway, Anderson
$245,000
20 ac of Large tract being sold off in 2 ac lots for commercial.

Lot1 N 29 Highway, Anderson
2838 S Main Street, Anderson
$390,000
Commercial land offering! This commercial land is one acre of fenced property with ample parking space. This property was previously restaurants prior to a fire. This property would be ideal for a business, warehouse, or storage facility. So much potential in this area! Offered for $390,000

2838 S Main Street, Anderson
R-1-A Destination Boulevard, Anderson
$585,100
Desirable high traffic property located right at I-85 and US 76-28 (Exit 19A) intersection. Great location for restaurant, corporate office, shopping plaza, wedding venue and many other business locations. More than 50,000 vehicles pass here each day. Exit 19B heading north t15 miles takes you to Clemson University, Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, boat ramps, shopping centers, hotels, fast food and dine in restaurants, residential home and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others.

R-1-A Destination Boulevard, Anderson
105 Destination Boulevard, Anderson
$949,000
249' along I-85! Desirable high traffic property located right at I-85 and US 76-28 (Exit 19A) intersection. Great location for restaurant, corporate office, shopping plaza, wedding venue and many other business locations. More than 50,000 vehicles pass here each day. Exit 19B heading north t15 miles takes you to Clemson University, Anderson serves 6 Georgia counties for food, entertainment and shopping and is growing at a healthy rate! Nearby properties include beautiful Lake Hartwell, boat ramps, shopping centers, hotels, fast food and dine in restaurants, residential home and condos. Other large employers include Michelin, Arthrex, Ryobi, Electrolux, First Quality, Walgreens Distribution and many others.

105 Destination Boulevard, Anderson

The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated

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